ANTIBODY SERVICES / ANTIBODY PURIFICATIONS

Antibody Purifications

On a daily bases, we run high-quality antibody purifications on our modern ÄKTA HPLC machines, with robust ISO-9001:2015 quality-assured protocols. The starting material is generally antiserum, egg yolk (IgY) or conditioned media (bioreactor harvests).

Our high-quality services in antibody purification include:  

  • IgG-purification of antiserum or culture media, using protein A or G column depending on origin/host of sample

  • IgY-purification of egg yolks. Our test-batches are generally run on eight egg yolks.

  • Affinity purification using antigen-coupled column. We couple and assemble a column for you with your antigen (peptide, protein or other molecule), followed by purifying your sample using the column. Your antigen-coupled column are robust and can generally be re-usable.

  • Extracting extra pure antibodies for ADA-assays, i.e. absorbing the fraction of anti-drug antibodies against the constant regions of the antigens of antibody-based drug candidates.

  • Purification of phospho-specific or aceylation-specific antibodies by negative and positive affinity purification

You decide in which buffer you would like your purified antibody, and on request we add preservative at no extra cost. A certificate outlining the final product specification, and a QC-ELISA result with curve and titer-value, is supplied with your purified antibody. 

Capra Science Antibodies in life-saving application

For your security, all our antibodies are developed under our ISO9001:2015 quality certification. Many of the antibodies we develop are used in life-saving applications. The most common applications are:    

  •        Diagnostic kits

  •        Assisting in the development of new drugs; i.e. by providing key-antibodies for ADA-assays in preclinical and clinical trials

  •        Detection of target/molecule of interest in groundbreaking research projects

  •        Development of nanobody-based drug candidates for humanization within the area of biological medicine

What makes us different

  • Capra Science Organic Farm is located in southern Sweden.

    We are proud to say that Swedish authorities have some of the strictest regulations worldwide for animal keeping, ethics and the environment.

    In addition we have chosen to be ISO 9001 as well as organically certified. Our farm is certified organic since many years back and has been awarded multiple times for outstanding animal care.

  • Our top priority is to promote healthy animals with strong immune systems.

    A strong immune system will give substantially higher levels of antigen-specific antibodies in serum upon an antigen challenge. 

  • We have developed unique and gentle immunization programs. The programs are adapted to each host and optimized for a generous production of antigen-specific antibodies.

  • The entire chain of events in antibody production and downstream processes take place onsite. We have a purpose-built organic farm as well as laboratories. We don't work with subcontractors. This guarantees a high level of quality assurance and IP security.

Top 7 reasons to work with us

  1. Expertise. Our advanced laboratory, in-depth knowledge and robust protocols guarantee the best performing antibodies. The antibody expertise of our staff will be within your reach throughout your project.

  2. Discretion. Your project is safe with us. The whole chain of events in your antibody production and downstream processes are done at Capra Science’s own farm and laboratories with no subcontractors.

  3. Quality. Capra Science holds an ISO 9001 quality assurance to guarantee top product quality.

  4. Cost-efficiency. Our unique animal care program has been optimized to yield a high titer antiserum.

  5. Ethical standards. Animal welfare is our top priority. We run 1st class award-winning animal care facilities at our purpose-built organic farm.

  6. Flexibility. Your antibody production is customized to meet your specific needs.

  7. Personal service. A project with us includes free expert email consultation throughout your antibody production. We enjoy the personal contact with every client. Our scientific curiosity and nerdy ambition to continuously learn and improve, make us good listeners and allow us to deliver exactly what you need.